The 2022 NC Open will be held over Thanksgiving Weekend from 25-27 November 2022 in Charlotte, NC, USA. The NCO features a $11,000 guaranteed prize fund in 8 US Chess rated sections: Championship (1900+), U1900, U1700, U1500, U1300 and U1100. The event runs alongside the 2022 US Masters, a national event featuring the top players in the Americas.
Current starting rank list of players of the main NC Open Championship 2022:
| Name | Rating | |
| 1 | BOB HOLLIMAN | 2200 |
| 2 | JASON MCKINNEY | 2126 |
| 3 | DIEGO ZILLERUELO | 2124 |
| 4 | MICHAEL WANG | 2056 |
| 5 | ROSHAN SETHURAMAN | 2025 |
| 6 | JACOB STOLL | 2018 |
| 7 | SRITEJ SATTARU | 2012 |
| 8 | PATRICK SCIACCA | 2007 |
| 9 | RAHUL RAMESH | 1980 |
| 10 | ASHA KUMAR | 1975 |
| 11 | VISHNUSANKAR JONNALAGADDA | 1938 |
| 12 | ARJUN SRINIVASAN | 1926 |
| 13 | SANJAY KUMAR | 1925 |
| 14 | MARIUS CUTITARU | 1917 |
| 15 | KEVIN KELLINSKY-GONZALEZ | 1916 |
| 16 | AKSHAT SURESH | 1915 |
| 17 | WFM KAREN HOSHINO | 1911 |
| 18 | DHRUV RAJAGANESH | 1909 |
| 19 | RISHI JASTI | 1899 |
| 20 | ADITYA RAMKUMAR | 1864 |
| 21 | PATRICK KENGSOONTRA | 1860 |
| 22 | YANIRA RIVERA NEGRON | 1833 |
| 23 | ANGEL SPIELVOGEL | 1833 |
| 24 | MATHEW JIANG | 1831 |
| 25 | NIRAV NATHA | 1830 |
| 26 | ALEX CHU | 1828 |
| 27 | ALAN CHEN | 1821 |
| 28 | MARIO PINEDA-BERMUDEZ | 1820 |
| 29 | ARAV GOLDSTEIN | 1820 |
| 30 | LEO CHANG | 1813 |
| 31 | SMAYAN AMMASANI | 1813 |
| 32 | NOSHIR PATEL | 1813 |
| 33 | TYLER SCHMUGGEROW | 1812 |
| 34 | YOGYA KONERU | 1806 |
